Risks of higher levels of inflammation
hsCRP (high-sensitivity C-Reactive Protein) is an established marker of systemic inflammation.
Higher levels of inflammation may increase risk of heart disease, cancer, and Alzheimer’s disease.
Higher levels of inflammation have been associated with greater symptoms of fatigue, depression, rheumatoid arthritis, migraine, Crohn’s disease, and Irritable Bowel Syndrome.
Category | hsCRP/CRP based risk* | Data to support |
Heart disease | hsCRP >0.5mg/L: people with hsCRP >0.5mg/L had an increased risk of cardiovascular disease, as shown in two clinical studies
hsCRP >1mg/L: hsCRP >1mg/L is used in clinical practice as the threshold for increased risk of cardiovascular disease
hsCRP >3mg/L: hsCRP >3mg/L is used in clinical practice as the threshold for “high risk” of cardiovascular disease | |
Cancer | hsCRP >1mg/L: people with hsCRP >1mg/L had a higher risk of cancer of any type, as shown in multiple clinical studies | |
Alzheimer’s disease | hsCRP>1.5mg/L: Adults <65 years old with an hsCRP > 1.5 mg/L had an increased risk of developing all cause dementia (dementia, Alzheimer’s disease, and vascular dementia), per a clinical study Note - Higher hsCRP in older adults (e.g., 70.6-94 years old) has been shown to be protective against Alzheimer’s Disease. | |
Fatigue | hsCRP>1mg/L: People with hsCRP >1mg/L were more likely to develop new onset fatigue, as shown in two clinical studies | |
Depression | hsCRP >3mg/L: people with hsCRP >3mg/L had greater depression severity, per a summary across multiple studies
Higher hsCRP levels were associated with symptoms of fatigue, restless sleep, low energy, concentration difficulties, poor psychomotor speed, and poor executive functioning | Reference 1 |
Rheumatoid Arthritis | hsCRP=2-8mg/L: hs-CRP of 2–8 mg/L was predictive of disease activity in Rheumatoid Arthritis, with higher activity relative to hsCRP<2mg/L, per a clinical study | Reference 1 |
Migraine | hsCRP 10-20mg/L: People with hsCRP between 10-20mg/L had an increased risk of developing chronic migraine (i.e., fulfilled the criteria for migraine and reported headache >or= 15 days/month) compared to those with lower levels, per a clinical study | Reference 1 |
Crohn’s Disease | CRP>20mg/L: CRP >20mg/L may help predict relapse within 6 weeks, per a clinical study
Note - CRP alone does not typically predict Crohn’s disease relapse. | |
IBS | Higher hsCRP levels were associated with greater disease severity, per a clinical study | Reference 1 |
*Be Golden helps you measure your hsCRP. hsCRP and CRP (C Reactive Protein) measure the same molecule (CRP) but hsCRP can measure trace amounts of it.
BE GOLDEN DOES NOT PROVIDE MEDICAL SERVICES OR ADVICE.
The information, including but not limited to text, graphics, images and other material contained on Be Golden's website and provided through Be Golden's products and services are for informational purposes only. Be Golden's products and services have not been evaluated by the U.S. Food and Drug Administration. No information on Be Golden's website or provided through Be Golden's products or services (a) contain or constitute, and should not be interpreted as, medical advice or opinion; and (b) are intended to diagnose, treat or cure disease. We specifically disclaim any express or implied warranties or merchantable quality, performance, suitability or merchantability of fitness for any particular usage, application or purpose of any laboratory tests arranged for you or test kits provided to you. No information on Be Golden's website or provided through Be Golden's products or services are a substitute for professional medical advice, diagnosis or treatment, and your use of Be Golden’s products or services does not create any provider-patient relationship. Always seek the advice of your physician or another licensed health care provider with any questions you may have regarding your health and before undertaking a new regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on Be Golden's website or through Be Golden's products or services. If you think you have a medical emergency, call 911.
Certain content provided on this website include links to third party websites (“Third-Party Websites”). We have no control over the content or performance of Third-Party Websites, and Be Golden does not represent, warrant or endorse any Third-Party Website, or the accuracy, fitness, lawfulness or quality of the information or material available through Third-Party Websites. Be Golden disclaims, and you agree to assume, all responsibility and liability for any damages or other harm resulting from your use of or reliance on, any content, advertisements or other resources available on any Third-Party Websites, regardless of whether we directly or indirectly link to such content, advertisement or other resources.